{"id":968,"date":"2020-10-18T11:30:20","date_gmt":"2020-10-18T08:30:20","guid":{"rendered":"http:\/\/demo.safirtema.com\/anka\/?p=968"},"modified":"2020-10-18T11:30:20","modified_gmt":"2020-10-18T08:30:20","slug":"remdesivir-ureticisi-gileaddan-dsoye-tepki","status":"publish","type":"post","link":"https:\/\/balikesirobjektif.com\/index.php\/2020\/10\/18\/remdesivir-ureticisi-gileaddan-dsoye-tepki\/","title":{"rendered":"Remdesivir \u00fcreticisi Gilead\u2019dan DS\u00d6\u2019ye tepki"},"content":{"rendered":"

ABD\u2019li ila\u00e7 \u015firketi Gilead, D\u00fcnya Sa\u011fl\u0131k \u00d6rg\u00fct\u00fc’n\u00fcn (WHO) Covid-19 ilac\u0131 remdesivirin hastaneye yat\u0131r\u0131lan hastalara yard\u0131mc\u0131 olmad\u0131\u011f\u0131 sonucuna varan \u00a0raporunun bulgular\u0131n\u0131 sorgulad\u0131.<\/p>\n

\u015eirket taraf\u0131ndan Reuters’a yap\u0131lan a\u00e7\u0131klamada DS\u00d6 raporunun verilerinin tutars\u0131z oldu\u011fu \u00a0ve erken a\u015fama testlerin sonu\u00e7lar\u0131na dayand\u0131\u011f\u0131 belirtildi. Gilead ayr\u0131ca remdesivi ilac\u0131n\u0131n kritik hastalardaki sonu\u00e7lar\u0131n\u0131n d\u00fcnyadan\u0131n pek \u00e7ok yerinde ba\u011f\u0131ms\u0131z ara\u015ft\u0131rmac\u0131lar taraf\u0131ndan ger\u00e7ekle\u015ftirilen klinik \u00e7al\u0131\u015fmalarla do\u011fruland\u0131\u011f\u0131n\u0131 vurgulad\u0131.<\/p>\n

ETK\u0130S\u0130 KANITLANAN \u0130LA\u00c7LARIN BA\u015eINI \u00c7EK\u0130YOR<\/strong><\/p>\n

ABD Ba\u015fkan\u0131 Donald Trump\u2019\u0131n corona vir\u00fcs tedavisinde de kullan\u0131lan remdevisir, stereoid ilac\u0131 deksametazon ile birlikte hen\u00fcz bir a\u015f\u0131n\u0131n bulunmad\u0131\u011f\u0131 pandemiye kar\u015f\u0131 etkisi kan\u0131tlanan ila\u00e7lar\u0131n ba\u015f\u0131n\u0131 \u00e7ekiyor. Ebolaya kar\u015f\u0131 \u00fcretilen ilaca ili\u015fkin ABD ve \u0130ngiltere\u2019de yap\u0131lan \u00a0ABD\u2019de ila\u00e7la ilgili yap\u0131lan klinik \u00e7al\u0131\u015fmalarda a\u011f\u0131r Covid-19 hastalar\u0131n\u0131n oksijen deste\u011fine ihtiyac\u0131 azaltt\u0131\u011f\u0131 ve hastanede kalma s\u00fcresini 5 g\u00fcne kadar k\u0131saltmaya yard\u0131mc\u0131 oldu\u011fu g\u00f6r\u00fcld\u00fc. S\u00f6z konusu ila\u00e7 Amerikan G\u0131da ve \u0130la\u00e7 \u0130daresi (FDA) taraf\u0131ndan May\u0131s ay\u0131nda acil kullan\u0131m onay\u0131 ald\u0131.<\/p>\n<\/p>\n

ABD Ba\u015fkan\u0131 Donald Trump’\u0131n tedavisinde remdevisir, deksametazon ve Regeneron’un antikor kokteyli kullan\u0131ld\u0131.<\/span> <\/div>\n

DS\u00d6: BULGULARIMIZ KES\u0130N, ETK\u0130S\u0130 SINIRLI YA DA H\u0130\u00c7 ETK\u0130S\u0130 YOK<\/strong><\/p>\n

Ancak, DS\u00d6, d\u00fcn yapt\u0131\u011f\u0131 a\u00e7\u0131klamada Covid-19 hastalar\u0131n\u0131 tedavi etmek i\u00e7in kullan\u0131lan ila\u00e7lar\u0131n inceleni\u011fi ve “Solidarity” (Dayan\u0131\u015fma) ad\u0131 verdi\u011fi \u00e7al\u0131\u015fmas\u0131nda remdesivirin, 28 g\u00fcn boyunca uygulanan tedavi kapsam\u0131nda hastanede kal\u0131\u015f s\u00fcresi \u00fczerinde \u00e7ok az etkisi oldu\u011fu veya hi\u00e7 etkisi olmad\u0131\u011f\u0131 sonucuna vard\u0131\u011f\u0131n\u0131 a\u00e7\u0131klad\u0131. <\/p>\n

DS\u00d6 \u00e7al\u0131\u015fmas\u0131 30’dan fazla \u00fclkede 11 bin .266 yeti\u015fkin hastada ger\u00e7ekle\u015ftirildi ve kurulu\u015f\u00a0 bulgular\u0131n\u0131n kesin kan\u0131tlara dayand\u0131\u011f\u0131n\u0131 s\u00f6yledi. <\/p>\n

Gilead ise, \u00a0bir plasebo ile kar\u015f\u0131la\u015ft\u0131r\u0131lan bin 062 hasta dahil olmak \u00fczere di\u011fer remdesivir denemelerinin, tedavinin Covid-19 \u00a0iyile\u015fme s\u00fcresini k\u0131saltt\u0131\u011f\u0131n\u0131 g\u00f6sterdi\u011fini s\u00f6yledi.<\/p>\n<\/p>\n

DS\u00d6’n\u00fcn \u00e7al\u0131\u015fmas\u0131 hen\u00fcz g\u00f6zden ge\u00e7irilmedi.<\/span> <\/div>\n

GILEAD: DS\u00d6’N\u00dcN VER\u0130LER\u0130 TUTARSIZ, BA\u011eIMSIZ KURULU\u015eLAR \u0130LACIN ETK\u0130S\u0130N\u0130 KANITLADI<\/strong><\/p>\n

Reuters’e verdi\u011fi deme\u00e7te Gilead, “Ortaya \u00e7\u0131kan DS\u00d6, verileri tutars\u0131z g\u00f6r\u00fcn\u00fcyor ve remdesivirin klinik yarar\u0131n\u0131 do\u011frulayan hakemli dergilerde yay\u0131nlanan \u00e7ok say\u0131da randomize, kontroll\u00fc \u00e7al\u0131\u015fmadan elde edilen daha sa\u011flam kan\u0131tlarla \u00e7eli\u015fiyor\u201d ifadelerini kullland\u0131. Gilead ayr\u0131ca, DS\u00d6 denemesinin, b\u00f6lgeden b\u00f6lgeye ve ilac\u0131 alan hastalar aras\u0131nda nas\u0131l y\u00fcr\u00fct\u00fcld\u00fc\u011f\u00fcne ili\u015fkin farkl\u0131l\u0131klar dedi\u011fi g\u00f6z \u00f6n\u00fcnde bulunduruldu\u011funda “kesin bulgular\u0131n elde edilip edilemeyece\u011finin net olmad\u0131\u011f\u0131n\u0131” bildirdi.<\/p>\n

DS\u00d6’N\u00dcN RAPORUNA G\u00d6RE REMDES\u0130V\u0130R DI\u015eINDAK\u0130 \u0130LA\u00c7LAR DA \u0130\u015eE YARAMIYOR<\/strong><\/p>\n

DS\u00d6\u2019nin \u201cSolidarity\u201d raporu, ayr\u0131ca corona vir\u00fcse kar\u015f\u0131 kullan\u0131lan hidroksiklorokin, anti-HIV ila\u00e7 kombinasyonu olan \u00a0lopinavir \/ ritonavir ve interferonu da de\u011ferlendirdi ve bunlar\u0131n da remdesivir gibi hastalar\u0131n hayatta kalmas\u0131na veya hastaneden daha h\u0131zl\u0131 \u00e7\u0131kmas\u0131na yard\u0131mc\u0131 olmak i\u00e7in \u00e7ok fazla etkili olmad\u0131\u011f\u0131 sonucuna vard\u0131.<\/p>\n

Di\u011fer taraftan, DS\u00d6 \u00e7al\u0131\u015fmas\u0131n\u0131n sonu\u00e7lar\u0131 hen\u00fcz bilim insanlar\u0131 taraf\u0131ndan g\u00f6zden ve \u00f6n bask\u0131 sunucusu medRxiv’ adl\u0131 bilimsel makale sitesine y\u00fcklendi.<\/p>\n

NEM, corona vir\u00fcs\u00fcN YAYILMASINDA ETK\u0130L\u0130 M\u0130?<\/strong><\/span><\/p><\/p>\n","protected":false},"excerpt":{"rendered":"

ABD\u2019li ila\u00e7 \u015firketi Gilead, D\u00fcnya Sa\u011fl\u0131k \u00d6rg\u00fct\u00fc’n\u00fcn (WHO) Covid-19 ilac\u0131 remdesivirin hastaneye yat\u0131r\u0131lan hastalara yard\u0131mc\u0131 olmad\u0131\u011f\u0131 sonucuna varan \u00a0raporunun bulgular\u0131n\u0131 sorgulad\u0131.<\/p>\n","protected":false},"author":1,"featured_media":969,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[415,419,162,53,420],"class_list":["post-968","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-saglik","tag-dso","tag-etkisi","tag-hasta","tag-ilac","tag-tedavi"],"_links":{"self":[{"href":"https:\/\/balikesirobjektif.com\/index.php\/wp-json\/wp\/v2\/posts\/968","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/balikesirobjektif.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/balikesirobjektif.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/balikesirobjektif.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/balikesirobjektif.com\/index.php\/wp-json\/wp\/v2\/comments?post=968"}],"version-history":[{"count":1,"href":"https:\/\/balikesirobjektif.com\/index.php\/wp-json\/wp\/v2\/posts\/968\/revisions"}],"predecessor-version":[{"id":972,"href":"https:\/\/balikesirobjektif.com\/index.php\/wp-json\/wp\/v2\/posts\/968\/revisions\/972"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/balikesirobjektif.com\/index.php\/wp-json\/wp\/v2\/media\/969"}],"wp:attachment":[{"href":"https:\/\/balikesirobjektif.com\/index.php\/wp-json\/wp\/v2\/media?parent=968"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/balikesirobjektif.com\/index.php\/wp-json\/wp\/v2\/categories?post=968"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/balikesirobjektif.com\/index.php\/wp-json\/wp\/v2\/tags?post=968"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}